Fate Therapeutics’ current part 1 knowledge for FT516 showed comparatively quicker relapses vs already approved autologous CAR-Ts. However, other manufacturers, like Allogene for their allogenic CAR-T therapy ALLO-501A, are exploring novel lymphodepletion approaches to enhance persistence of allogenic cells. Nevertheless, allogenic NKs demonstrate a robust worth proposition relative to their T cell counterparts as a outcome of comparable response rates mixed with the added advantage of a considerably safer AE profile.
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